Curbing Inflammation May Reduce Heart Disease Risk
It has been established in prior studies that if one has an inflammatory condition such as psoriasis, for example, the risk of heart disease increases substantially. A pro-inflammatory agent called tumor necrosis factor (TNF) tends to be elevated in patients with many inflammatory conditions such as psoriasis and rheumatoid arthritis. Prior studies have shown us that when patients took medication that act again TNF, the risk of heart disease decreased (J Am Acad Dermatol 2005; 52:262).
A recent study in Norway looked at patients with 3 different inflammatory conditions: rheumatoid arthritis, ankylosing spondylitis, and psoriatic arthritis. Patients were treated with TNF antagonists and aortic stiffness was assessed as a marker of heart disease. It was found that those receiving anti-TNF agents as compared to placebo had statistically significant decreases in aortic stiffness and C-reactive protein levels (a marker for heart diseaes). Although the study was of small sample size and of short duration, it can be concluded that TNF-antagonists may potentially decrease heart disease risk.
Medications that are TNF antagonists have a wide and potentially detrimental side effect profile and need to be prescribed judiciously. There are an array of natural treatments that can be catered to one's condition that can potentially lower TNF and cardio-CRP levels as well.
This is an important study in that it substantiates the fact that decreasing inflammation in our bodies will help reduce cardiovascular risk. This can be done via a number of fronts depending on one's unique inflammatory condition.
source: Angel K et al. Tumor necrosis factor-{alpha} antagonists improve aortic stiffness in patient with inflammatory arthropathies: A controlled study. Hypertension 2010 Feb; 55:333.
Time exhibited a wonderful and potentially life saving article on inflammation and its ties to heart disease in 2005. I highly recommend this read. www.time.com/time/magazine/article/0,9171,993419,00.html
A recent study in Norway looked at patients with 3 different inflammatory conditions: rheumatoid arthritis, ankylosing spondylitis, and psoriatic arthritis. Patients were treated with TNF antagonists and aortic stiffness was assessed as a marker of heart disease. It was found that those receiving anti-TNF agents as compared to placebo had statistically significant decreases in aortic stiffness and C-reactive protein levels (a marker for heart diseaes). Although the study was of small sample size and of short duration, it can be concluded that TNF-antagonists may potentially decrease heart disease risk.
Medications that are TNF antagonists have a wide and potentially detrimental side effect profile and need to be prescribed judiciously. There are an array of natural treatments that can be catered to one's condition that can potentially lower TNF and cardio-CRP levels as well.
This is an important study in that it substantiates the fact that decreasing inflammation in our bodies will help reduce cardiovascular risk. This can be done via a number of fronts depending on one's unique inflammatory condition.
source: Angel K et al. Tumor necrosis factor-{alpha} antagonists improve aortic stiffness in patient with inflammatory arthropathies: A controlled study. Hypertension 2010 Feb; 55:333.
Time exhibited a wonderful and potentially life saving article on inflammation and its ties to heart disease in 2005. I highly recommend this read. www.time.com/time/magazine/article/0,9171,993419,00.html
Living Smarter, Living Longer,
Dr. Kroner
Posted by Zina Kroner at 4/27/2010 6:46 PM 
Categories: Nutrition, Heart Health, Rheumatology
Tags: psoriasis ankylosing spondylitis integrative medicine inflammation holistic medicine alternative medicine zina kroner tumor necrosis factor rheumatoid arthritis TNF antagonists best internist heart disease prevention methotrexate internal medicine in New YOrk Best internist in manhattan Time magazine
Categories: Nutrition, Heart Health, Rheumatology
Tags: psoriasis ankylosing spondylitis integrative medicine inflammation holistic medicine alternative medicine zina kroner tumor necrosis factor rheumatoid arthritis TNF antagonists best internist heart disease prevention methotrexate internal medicine in New YOrk Best internist in manhattan Time magazine
Fantastic BLOGs Dr. Kroner > Thank YOU !
Please keep them coming !
If I may expound on your Inflammation Message…
Today, The Fires of Inflammation are raging all over our Bodies & Brains (Autism ?).
Under normal conditions, Inflammation's hallmark signs -- redness, swelling, soreness, and warmth -- stay localized and disappear as the injury or infection heals.
But sometimes the immune system does not shut off, instead releasing a stream of inflammation-promoting compounds that spread throughout the body, damaging cells and tissues
Chronic Inflammation …
Chronic, UnResolved / UnTreated Inflammation spurred by an Immune System Over-Load > Is now considered a Key Cause / Factor in almost ALL Chronic Degenerative and LifeStyle Diseases.
Chronic SILENT Inflammation remains below the Threshold of Pain
The chronic and continuous low-level demand that silent inflammation places on the body's defense systems results in an immune-system breakdown.
If left unchecked, low-level systemic inflammation can simmer for years, contributing to a range of seemingly unrelated ailments
Consider / Connect …
> The Chronic Inflammation DOTs of “ Classic” Achooo > ALLERGY Disease.
Beginning at Birth for 1 in 3 INFANTs > Allergy Disease sets in motion a lifetime of sequence of predictable Diseases ( termed Allergy MARCH ) which in great probability will mitigate to Allergic ASTHMA …
And beyond Allergic ASTHMA > a Lifetime, Slippery Slope of Allergy Driven Diseases and compromised Quality of Life ( Achoo & Ouch ) !
ALLERGY = is a Corrosive > A 24 / 7 / 365 / A LifeTime > Cumulative, Progressive, Chronic INFLAMMATION, Auto-Immune Disease.
Your Immune System has only so much Disease Fighting Capacity ….
Why not FREE UP Immune System Fighting Capacity > From the 24 / 7 / 52 / A Lifetime of Inflammation caused by Fighting Harmless Allergens…
Extinguish your ALLERGY Inflammation Fires …
HOW ?
A visit to your Primary Care Dr. for Self Administered, Immuno-Allergy DROPs > Which are Custom Formulated specifically to Neutralize each of YOUR Blood Test ID’ed / Geo-Regional, Seasonal & Year-round Offending allergens…
Your Custom immuno-Allergy DROPs > Will Neutralize the SOURCE of Your Chronic Inflammatory Allergy FIREs…
Producing Lasting, If Not Lifetime Health & Quality of Life Benefits that come with being Free of Allergy Disease.
FAR to many People suffer from Allergies .. taking Allergy Med’s that make them feel awful and only mask Symptoms …
Leaving the progression of Allergy Disease InTact to Continue / Exacerbate UnAbated…
Let us work toward extinguishing these Inflammation Fires against silly Enviro / Harmless Allergens …
Best Health = Wealth Regards,
Stephen
DropYourAllergies.com
BLOG Readers BOOK Suggestion:
The Autoimmune Epidemic:
Bodies Gone Haywire in a World out of Balance -- and the Cutting Edge Science that Promises Hope
Author: Donna Jackson Nakazawa
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Yes, Stephen. I agree with your comment. Remember that there are many markers of inflammation in the bloodstream that can be routinely measured, such as TNF, cardio-CRP, etc. Inflammation can also be measured by how someone feels and whether or not their particular inflammatory condition is flaring up.
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What are the causes of heart disease? and How can it be prevented?
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Thanks for the warning about the link between inflammation and increased risks of cancer, heart disease, and Alzheimer's. I have hereditary risk for all three of these, and it's good to know that I can avoid exacerbating that risk by paying attention to inflammation and using natural and pharmaceutical means to lower TNF.
Thanks for the personally valuable information.
Uncle Jack
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Thank you for sharing this useful information on this blog. Was searching for the information related to cancer and found this information. It is better to have good knowledge regarding this dreadful ailment.
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